RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-24-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; immunofluorescence etc.
Target
FURIN
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-24 regulates cardiac fibrosis after myocardial infarction
Year
2012
Function
"TGF-beta (a pathological mediator of fibrotic disease) increased miR-24 expression, overexpression of miR-24 reduced TGF-beta secretion and smad2/3 phosphorylation in cardiac fibroblasts (CFs)."